Distinct populations of tumor-initiating cells derived from a tumor generated by rat mammary cancer stem cells

Tumors derived from rat LA7 cancer stem cells (CSCs) contain a hierarchy of cells with different capacities to generate self-renewing spheres and tubules serially ex vivo and to evoke tumors in vivo. We isolated two morphologically distinct cell types with distinct tumorigenic potential from LA7-evo...

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Detalhes bibliográficos
Main Authors: Zucchi, I., Astigiano, S., Bertalot, G., Sanzone, S., Cocola, C., Pelucchi, P., Bertoli, G., Stehling, M., Barbieri, O., Albertini, A., Schöler, H. R., Neel, B. G., Reinbold, R. A., Dulbecco, R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575224/
https://ncbi.nlm.nih.gov/pubmed/18957543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808978105
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