Protection against malaria in Aotus monkeys immunized with a recombinant blood-stage antigen fused to a universal T-cell epitope: correlation of serum gamma interferon levels with protection.

The major surface antigen p190 of the human malaria parasite Plasmodium falciparum contains nonpolymorphic, immunogenic stretches of amino acids which are attractive components for a subunit vaccine against malaria. One such polypeptide, termed 190L, is contained in the 80-kDa processing product of...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Herrera, M A, Rosero, F, Herrera, S, Caspers, P, Rotmann, D, Sinigaglia, F, Certa, U
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257516/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1370271/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.1.154-158.1992
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