The Atg8 Conjugation System Is Indispensable for Proper Development of Autophagic Isolation Membranes in Mice

Autophagy is an evolutionarily conserved bulk-protein degradation pathway in which isolation membranes engulf the cytoplasmic constituents, and the resulting autophagosomes transport them to lysosomes. Two ubiquitin-like conjugation systems, termed Atg12 and Atg8 systems, are essential for autophago...

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Autors principals: Sou, Yu-shin, Waguri, Satoshi, Iwata, Jun-ichi, Ueno, Takashi, Fujimura, Tsutomu, Hara, Taichi, Sawada, Naoki, Yamada, Akane, Mizushima, Noboru, Uchiyama, Yasuo, Kominami, Eiki, Tanaka, Keiji, Komatsu, Masaaki
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2008
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575156/
https://ncbi.nlm.nih.gov/pubmed/18768753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-03-0309
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