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A Novel Class of mRNA-containing Cytoplasmic Granules Are Produced in Response to UV-Irradiation

Nucleic acids are substrates for different types of damage, but little is known about the fate of damaged RNAs. We addressed the existence of an RNA-damage response in yeast. The decay kinetics of GAL1p-driven mRNAs revealed a dose-dependent mRNA stabilization upon UV-irradiation that was not observ...

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Autori principali: Gaillard, Hélène, Aguilera, Andrés
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575145/
https://ncbi.nlm.nih.gov/pubmed/18768757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-02-0193
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