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Post-exposure Targeting of Specific Epitopes on Ricin Toxin Abrogates Toxin-induced Hypoglycemia, Hepatic Injury and Lethality in a Mouse Model

The role of the liver in fatal intoxication with the binary toxin ricin is undefined. Means to reverse pathological events in the liver and to gain host survival after exposure to this toxin have not been described. We report a robust 7/4(+) neutrophil influx into the liver of C57BL/6 mice after par...

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Detalhes bibliográficos
Main Authors: Roche, James K., Stone, Matthew K., Gross, Lisa K., Lindner, Matthew, Seaner, Regina, Pincus, Seth H., Obrig, Tom G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575142/
https://ncbi.nlm.nih.gov/pubmed/18779782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2008.83
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