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Estradiol attenuates neuroprotective benefits of isoflurane preconditioning in ischemic mouse brain

Isoflurane preconditioning (IsoPC) neuroprotection in experimental stroke is male-specific. We determined whether estradiol alters ischemic outcomes in IsoPC brain and examined the role of estrogen receptors (ERs). Seven to 10 days before preconditioning, ovariectomized (OVX) mice were implanted wit...

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Bibliografiske detaljer
Main Authors: Wang, Lan, Kitano, Hideto, Hurn, Patricia D, Murphy, Stephanie J
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575135/
https://ncbi.nlm.nih.gov/pubmed/18612317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2008.70
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