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Critical roles for macrophages in islet angiogenesis and maintenance during pancreatic degeneration

OBJECTIVE: Chronic pancreatitis, characterized by pancreatic exocrine tissue destruction with initial maintenance of islets, eventually leads to insulin-dependent diabetes in most patients. Mice deficient for the transcription factors E2F1 and E2F2 suffer from a chronic pancreatitis-like syndrome an...

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Detalhes bibliográficos
Main Authors: Tessem, Jeffery S., Jensen, Jan N., Pelli, Hanna, Dai, Xu-Ming, Zong, Xiao-Hua, Stanley, E. Richard, Jensen, Jan, DeGregori, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575065/
https://ncbi.nlm.nih.gov/pubmed/18375440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1577
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