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Automated error-tolerant macromolecular structure determination from multidimensional nuclear Overhauser enhancement spectra and chemical shift assignments: Improved robustness and performance of the PASD algorithm

We report substantial improvements to the previously introduced automated NOE assignment and structure determination protocol known as PASD. The improved protocol includes extensive analysis of input spectral data to create a low-resolution contact map of residues expected to be close in space. This...

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Autors principals: Kuszewski, John J., Thottungal, Robin Augustine, Schwieters, Charles D., Clore, G. Marius
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575051/
https://ncbi.nlm.nih.gov/pubmed/18668206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-008-9255-1
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