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Synaptic Vesicles Form by Budding from Tubular Extensions of Sorting Endosomes in PC12 Cells

The putative role of sorting early endosomes (EEs) in synaptic-like microvesicle (SLMV) formation in the neuroendocrine PC12 cell line was investigated by quantitative immunoelectron microscopy. By BSA-gold internalization kinetics, four distinct endosomal subcompartments were distinguished: primary...

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Detalhes bibliográficos
Main Authors: de Wit, Heidi, Lichtenstein, Yael, Geuze, Hans J., Kelly, Regis B., van der Sluijs, Peter, Klumperman, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25750/
https://ncbi.nlm.nih.gov/pubmed/10588650
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