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Induction of FLIP expression by androgens protects prostate cancer cells from TRAIL-mediated apoptosis

BACKGROUND: Prostate tumors initially regress in response to androgen-ablation therapy. However, most cancers eventually relapse with an androgen-depletion-independent (ADI) phenotype that is often more aggressive than the original androgen-dependent (AD) tumor. Importantly, most relapsed tumors sti...

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Hlavní autoři: Raclaw, Kristin A., Heemers, Hannelore V., Kidd, Emily M., Dehm, Scott M., Tindall, Donald J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574904/
https://ncbi.nlm.nih.gov/pubmed/18726983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.20844
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