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ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection
Exocytosis of lysosomes from macrophages has been described as a response to microbial cytotoxins and hemolysins, as well as for releasing proinflammatory cytokines interleukin (IL)-1β and IL-18 during inflammasome activation. The mycobacterial ESX-1 secretion system, encoded in part by the Region o...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574867/ https://ncbi.nlm.nih.gov/pubmed/18503637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2008.01177.x |
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