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ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection

Exocytosis of lysosomes from macrophages has been described as a response to microbial cytotoxins and hemolysins, as well as for releasing proinflammatory cytokines interleukin (IL)-1β and IL-18 during inflammasome activation. The mycobacterial ESX-1 secretion system, encoded in part by the Region o...

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Bibliografiske detaljer
Main Authors: Koo, Ingrid Chou, Wang, Chen, Raghavan, Sridharan, Morisaki, J. Hiroshi, Cox, Jeffery S., Brown, Eric J.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574867/
https://ncbi.nlm.nih.gov/pubmed/18503637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2008.01177.x
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