Luminal Heterodimeric Amino Acid Transporter Defective in Cystinuria

Mutations of the glycoprotein rBAT cause cystinuria type I, an autosomal recessive failure of dibasic amino acid transport (b(0,+) type) across luminal membranes of intestine and kidney cells. Here we identify the permease-like protein b(0,+)AT as the catalytic subunit that associates by a disulfide...

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Hauptverfasser: Pfeiffer, Rahel, Loffing, Jan, Rossier, Grégoire, Bauch, Christian, Meier, Christian, Eggermann, Thomas, Loffing-Cueni, Dominique, Kühn, Lukas C., Verrey, François
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC25748/
https://ncbi.nlm.nih.gov/pubmed/10588648
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