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L-Methionine Toxicity in Freshly-Isolated Mouse Hepatocytes is Gender-Dependent and Mediated in Part by Transamination
L-methionine (Met) has been implicated in parenteral nutrition-associated cholestasis in infants and, at high levels, causes liver toxicity by mechanisms that are not clear. In this study, Met toxicity was characterized in freshly-isolated male and female mouse hepatocytes incubated with 5-30 mM Met...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574759/ https://ncbi.nlm.nih.gov/pubmed/18552130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.141044 |
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