Variants in the Nicotinic Receptors Alter the Risk for Nicotine Dependence

OBJECTIVE: A recent study provisionally identified numerous genetic variants as risk factors for the transition from smoking to the development of nicotine dependence, including an amino acid change in the α5 nicotinic cholinergic receptor (CHRNA5). The purpose of this study is to replicate these fi...

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Detalhes bibliográficos
Main Authors: Bierut, Laura Jean, Stitzel, Jerry A., Wang, Jen C., Hinrichs, Anthony L., Grucza, Richard A., Xuei, Xiaoling, Saccone, Nancy L., Saccone, Scott F., Bertelsen, Sarah, Fox, Louis, Horton, William J., Morgan, Shawn D., Breslau, Naomi, Budde, John, Cloninger, C. Robert, Dick, Danielle M., Foroud, Tatiana, Hatsukami, Dorothy, Hesselbrock, Victor, Johnson, Eric O., Kramer, John, Kuperman, Samuel, Madden, Pamela A. F., Mayo, Kevin, Nurnberger, John, Pomerleau, Ovide, Porjesz, Bernice, Reyes, Oliver, Schuckit, Marc, Swan, Gary, Tischfield, Jay A., Edenberg, Howard J., Rice, John P., Goate, Alison M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574742/
https://ncbi.nlm.nih.gov/pubmed/18519524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2008.07111711
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