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Effects of a high daily dose of soy isoflavones on DNA damage, apoptosis and estrogenic outcomes in healthy, postmenopausal women - a Phase I clinical trial

OBJECTIVE: A Phase I double blinded clinical trial was conducted to evaluate the effects of a high oral dose of soy isoflavones administered daily for 84 days to healthy, postmenopausal women. Principal outcome measures included DNA damage, apoptosis and changes indicative of estrogenic stimulation....

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Bibliographic Details
Main Authors: Pop, Elena A., Fischer, Leslie M., Coan, April D., Gitzinger, Matt, Nakamura, Jun, Zeisel, Steven H.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574732/
https://ncbi.nlm.nih.gov/pubmed/18446090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/gme.0b013e318167b8f2
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