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Leishmania donovani infection in scid mice: lack of tissue response and in vivo macrophage activation correlates with failure to trigger natural killer cell-derived gamma interferon production in vitro.

Infection of immunocompetent mice with Leishmania donovani is characterized by the development of a tissue granulomatous response, in vivo macrophage activation, and a predominantly Th1-type CD4+ T-cell response. To determine whether a recently described T-cell-independent pathway of gamma interfero...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Kaye, P M, Bancroft, G J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257470/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1398944/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.10.4335-4342.1992
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