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Reduction of Disease Activity and Disability With High-Dose Cyclophosphamide in Patients With Aggressive Multiple Sclerosis

OBJECTIVE: To explore the safety and effectiveness of high-dose cyclophosphamide (HiCy) without bone marrow transplantation in patients with aggressive multiple sclerosis (MS). DESIGN: A 2-year open-label trial of patients with aggressive relapsing-remitting multiple sclerosis (RRMS) given an immuno...

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Bibliographic Details
Main Authors: Krishnan, Chitra, Kaplin, Adam I., Brodsky, Robert A., Drachman, Daniel B., Jones, Richard J., Pham, Dzung L., Richert, Nancy D., Pardo, Carlos A., Yousem, David M., Hammond, Edward, Quigg, Megan, Trecker, Carrilin, McArthur, Justin C., Nath, Avindra, Greenberg, Benjamin M., Calabresi, Peter A., Kerr, Douglas A.
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574697/
https://ncbi.nlm.nih.gov/pubmed/18541787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.65.8.noc80042
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