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Identifying significant covariates for anti-HIV treatment response: mechanism-based differential equation models and empirical semiparametric regression models
In this paper, the mechanism-based ordinary differential equation (ODE) model and the flexible semiparametric regression model are employed to identify the significant covariates for antiretroviral response in AIDS clinical trials. We consider the treatment effect as a function of three factors (or...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574674/ https://ncbi.nlm.nih.gov/pubmed/18407583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3272 |
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