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Identifying significant covariates for anti-HIV treatment response: mechanism-based differential equation models and empirical semiparametric regression models

In this paper, the mechanism-based ordinary differential equation (ODE) model and the flexible semiparametric regression model are employed to identify the significant covariates for antiretroviral response in AIDS clinical trials. We consider the treatment effect as a function of three factors (or...

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Detalhes bibliográficos
Main Authors: Huang, Yangxin, Liang, Hua, Wu, Hulin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574674/
https://ncbi.nlm.nih.gov/pubmed/18407583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3272
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