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CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels
High-conductance, Ca(2+)-activated and voltage-gated (BK) channels set neuronal firing. They are almost universally activated by alcohol, leading to reduced neuronal excitability and neuropeptide release and to motor intoxication. However, several BK channels are inhibited by alcohol, and most other...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574430/ https://ncbi.nlm.nih.gov/pubmed/16341213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1602 |
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