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Cation-specific structural accommodation within a catalytic RNA
Metal ions facilitate the folding of the hairpin ribozyme, but do not participate directly in catalysis. The metal complex cobalt (III) hexaammine supports folding and activity of the ribozyme and also mediates specific internucleotide photocrosslinks, several of which retain catalytic ability. Thes...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574416/ https://ncbi.nlm.nih.gov/pubmed/16411759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0513709 |
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