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Identification of tumor necrosis factor as a transcriptional regulator of the phosphoenolpyruvate carboxykinase gene following endotoxin treatment of mice.

The decreased synthesis of hepatic phosphoenolpyruvate carboxykinase (PEPCK), the rate-limiting enzyme of gluconeogenesis, that occurs during endotoxemia was shown previously in rats to occur at the transcriptional level. In the current study, the exogenous administration of human recombinant tumor...

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Pubblicato in:Infect Immun
Autori principali: Hill, M R, McCallum, R E
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1992
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257434/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1398916/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.10.4040-4050.1992
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