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BAY36-7620: a potent non-competitive mGlu1 receptor antagonist with inverse agonist activity
L-glutamate (Glu) activates at least eight different G protein-coupled receptors, the metabotropic glutamate (mGlu) receptors, which mostly act as regulators of synaptic transmission. These receptors consist of two domains: an extracellular one where agonists bind, and a transmembrane heptahelix reg...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Pharmacology and Experimental Therapeutics
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2573968/ https://ncbi.nlm.nih.gov/pubmed/11306677 |
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