Toll-Like Receptor-3 and Geographic Atrophy in Age-Related Macular Degeneration

BACKGROUND: Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment in the developed world. Advanced AMD is comprised of geographic atrophy (GA) and choroidal neovascularization (CNV). Specific genetic variants that predispose for GA are largely unknown. MET...

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Autori principali: Yang, Zhenglin, Stratton, Charity, Francis, Peter J., Kleinman, Mark E., Tan, Perciliz L., Gibbs, Daniel, Tong, Zongzhong, Chen, Haoyu, Constantine, Ryan, Yang, Xian, Chen, Yuhong, Zeng, Jiexi, Davey, Lisa, Ma, Xiang, Hau, Vincent S., Wang, Chi, Harmon, Jennifer, Buehler, Jeanette, Pearson, Erik, Patel, Shrena, Kaminoh, Yuuki, Watkins, Scott, Luo, Ling, Zabriskie, Norman A., Bernstein, Paul S., Cho, Wongil, Schwager, Andrea, Hinton, David R, Klein, Michael L, Hamon, Sara C., Simmons, Emily, Yu, Beifeng, Campochiaro, Betsy, Sunness, Janet S., Campochiaro, Peter, Jorde, Lynn, Parmigiani, Giovanni, Zack, Donald J., Katsanis, Nicholas, Ambati, Jayakrishna, Zhang, Kang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573951/
https://ncbi.nlm.nih.gov/pubmed/18753640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0802437
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