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Mutations in the SLC2A9 Gene Cause Hyperuricosuria and Hyperuricemia in the Dog
Allantoin is the end product of purine catabolism in all mammals except humans, great apes, and one breed of dog, the Dalmatian. Humans and Dalmatian dogs produce uric acid during purine degradation, which leads to elevated levels of uric acid in blood and urine and can result in significant disease...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2573870/ https://ncbi.nlm.nih.gov/pubmed/18989453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000246 |
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