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Colinearity of Reverse Transcriptase Inhibitor Resistance Mutations Detected by Population-Based Sequencing

High-level resistance to multiple drugs is often detected by directly sequencing uncloned polymerase chain reaction products (population-based sequencing). It is not known, however, if this method of identifying mutations gives an accurate picture of individual viral genomes. To determine how often...

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Bibliographische Detailangaben
Hauptverfasser: Gonzales, Matthew J., Johnson, Elizabeth, Dupnik, Kathryn M., Imamichi, Tomozumi, Shafer, Robert W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573396/
https://ncbi.nlm.nih.gov/pubmed/14615657
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