Identification and Characterization of the Plasmodium yoelii PyP140/RON4 Protein, an Orthologue of Toxoplasma gondii RON4, Whose Cysteine-Rich Domain Does Not Protect against Lethal Parasite Challenge Infection

Previously, we identified a Plasmodium yoelii YM 140-kDa merozoite protein, designated PyP140, which formed a complex with apical membrane antigen 1 (AMA1). Furthermore, we produced a nonprotective monoclonal antibody (MAb), 48F8, that immunoprecipitated metabolically labeled PyP140 and localized th...

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Bibliographische Detailangaben
Hauptverfasser: Narum, David L., Nguyen, Vu, Zhang, Yanling, Glen, Jacqueline, Shimp, Richard L., Lambert, Lynn, Ling, Irene T., Reiter, Karine, Ogun, Solabomi A., Long, Carole, Holder, Anthony A., Herrera, Raul
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573347/
https://ncbi.nlm.nih.gov/pubmed/18710865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01717-07
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