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Drosophila Maternal Hsp83 mRNA Destabilization Is Directed by Multiple SMAUG Recognition Elements in the Open Reading Frame

SMAUG (SMG) is an RNA-binding protein that functions as a key component of a transcript degradation pathway that eliminates maternal mRNAs in the bulk cytoplasm of activated Drosophila melanogaster eggs. We previously showed that SMG destabilizes maternal Hsp83 mRNA by recruiting the CCR4-NOT deaden...

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Hlavní autoři: Semotok, Jennifer L., Luo, Hua, Cooperstock, Ramona L., Karaiskakis, Angelo, Vari, Heli K., Smibert, Craig A., Lipshitz, Howard D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573300/
https://ncbi.nlm.nih.gov/pubmed/18794360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00037-08
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