With Minimal Systemic T-Cell Expansion, CD8(+) T Cells Mediate Protection of Rhesus Macaques Immunized with Attenuated Simian-Human Immunodeficiency Virus SHIV89.6 from Vaginal Challenge with Simian Immunodeficiency Virus

The presence, at the time of challenge, of antiviral effector T cells in the vaginal mucosa of female rhesus macaques immunized with live-attenuated simian-human immunodeficiency virus 89.6 (SHIV89.6) is associated with consistent and reproducible protection from pathogenic simian immunodeficiency v...

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Bibliographic Details
Main Authors: Genescà, Meritxell, Skinner, Pamela J., Hong, Jung Joo, Li, Jun, Lu, Ding, McChesney, Michael B., Miller, Christopher J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573271/
https://ncbi.nlm.nih.gov/pubmed/18787003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01433-08
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