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Antiretroviral Therapy prior to Acute Viral Replication Preserves CD4 T Cells in the Periphery but Not in Rectal Mucosa during Acute Simian Immunodeficiency Virus Infection

The rectal mucosa is a major site for human immunodeficiency virus entry and CD4 T-cell depletion. The early and near-total loss of these cells from the rectal mucosa severely compromises the ability of the mucosal immune system to control various opportunistic infections. Protecting these cells fro...

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Hlavní autoři: Kader, Muhamuda, Hassan, Wail M., Eberly, Matthew, Piatak, Michael, Lifson, Jeffrey D., Roederer, Mario, Mattapallil, Joseph J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573260/
https://ncbi.nlm.nih.gov/pubmed/18768962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01143-08
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