Tyrosine Phosphorylation of the Nuclear Receptor Coactivator AIB1/SRC-3 Is Enhanced by Abl Kinase and Is Required for Its Activity in Cancer Cells

Overexpression and activation of the steroid receptor coactivator amplified in breast cancer 1 (AIB1)/steroid receptor coactivator-3 (SRC-3) have been shown to have a critical role in oncogenesis and are required for both steroid and growth factor signaling in epithelial tumors. Here, we report a ne...

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Autori principali: Oh, Annabell S., Lahusen, John T., Chien, Christopher D., Fereshteh, Mark P., Zhang, Xiaolong, Dakshanamurthy, Sivanesan, Xu, Jianming, Kagan, Benjamin L., Wellstein, Anton, Riegel, Anna T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573238/
https://ncbi.nlm.nih.gov/pubmed/18765637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00118-08
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