Double-Stranded RNA Adenosine Deaminases Enhance Expression of Human Immunodeficiency Virus Type 1 Proteins

ADARs (adenosine deaminases that act on double-stranded RNA) are RNA editing enzymes that catalyze a change from adenosine to inosine, which is then recognized as guanosine by translational machinery. We demonstrate here that overexpression of ADARs but not of an ADAR mutant lacking editing activity...

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Main Authors: Phuphuakrat, Angsana, Kraiwong, Romchat, Boonarkart, Chompunuch, Lauhakirti, Darat, Lee, Tun-Hou, Auewarakul, Prasert
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Genome Replication and Regulation of Viral Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573204/
https://ncbi.nlm.nih.gov/pubmed/18753201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00238-08
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