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E6 Proteins from Multiple Human Betapapillomavirus Types Degrade Bak and Protect Keratinocytes from Apoptosis after UVB Irradiation

Human papillomavirus (HPV) types from the beta genus (beta-HPVs) have been implicated in the development of skin cancer. A potentially important aspect of their carcinogenic role is the ability of the E6 protein to degrade the proapoptotic family member Bak, which gives cells the ability to survive...

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Main Authors: Underbrink, Michael P., Howie, Heather L., Bedard, Kristin M., Koop, Jennifer I., Galloway, Denise A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573196/
https://ncbi.nlm.nih.gov/pubmed/18715924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00902-08
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