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Binding STAT2 by the Acidic Domain of Human Cytomegalovirus IE1 Promotes Viral Growth and Is Negatively Regulated by SUMO

The human cytomegalovirus (HCMV) 72-kDa immediate-early 1 (IE1) protein is thought to modulate cellular antiviral functions impacting on promyelocytic leukemia (PML) nuclear bodies and signal transducer and activator of transcription (STAT) signaling. IE1 consists of four distinct regions: an amino-...

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Detalhes bibliográficos
Main Authors: Huh, Yong Ho, Kim, Young Eui, Kim, Eui Tae, Park, Jung Jin, Song, Moon Jung, Zhu, Hua, Hayward, Gary S., Ahn, Jin-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573188/
https://ncbi.nlm.nih.gov/pubmed/18701593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00833-08
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