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Macrolide Antibiotic-Mediated Downregulation of MexAB-OprM Efflux Pump Expression in Pseudomonas aeruginosa

Macrolide antibiotics modulate the quorum-sensing system of Pseudomonas aeruginosa. We tested the effect of macrolide antibiotics on the cell density-dependent expression of the MexAB-OprM efflux pump and found that 1.0 μg/ml (MIC/6.25) of azithromycin suppressed the expression of MexAB-OprM by abou...

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Detaylı Bibliyografya
Asıl Yazarlar: Sugimura, Makoto, Maseda, Hideaki, Hanaki, Hideaki, Nakae, Taiji
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573159/
https://ncbi.nlm.nih.gov/pubmed/18676884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00511-08
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