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Macrolide Antibiotic-Mediated Downregulation of MexAB-OprM Efflux Pump Expression in Pseudomonas aeruginosa
Macrolide antibiotics modulate the quorum-sensing system of Pseudomonas aeruginosa. We tested the effect of macrolide antibiotics on the cell density-dependent expression of the MexAB-OprM efflux pump and found that 1.0 μg/ml (MIC/6.25) of azithromycin suppressed the expression of MexAB-OprM by abou...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2573159/ https://ncbi.nlm.nih.gov/pubmed/18676884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00511-08 |
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