KHM-1, a Novel Plasmid-Mediated Metallo-β-Lactamase from a Citrobacter freundii Clinical Isolate

A novel gene, bla(KHM-1), encoding a metallo-β-lactamase, KHM-1, was cloned from a clinical isolate of Citrobacter freundii resistant to most β-lactam antibiotics. Escherichia coli expressing bla(KHM-1) was resistant to all broad-spectrum β-lactams except for monobactams and showed reduced susceptib...

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Bibliografiske detaljer
Main Authors: Sekiguchi, Jun-ichiro, Morita, Koji, Kitao, Tomoe, Watanabe, Noboru, Okazaki, Mitsuhiro, Miyoshi-Akiyama, Tohru, Kanamori, Masato, Kirikae, Teruo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573105/
https://ncbi.nlm.nih.gov/pubmed/18765691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01337-07
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