Functional Polymorphisms in PRODH Are Associated with Risk and Protection for Schizophrenia and Fronto-Striatal Structure and Function

PRODH, encoding proline oxidase (POX), has been associated with schizophrenia through linkage, association, and the 22q11 deletion syndrome (Velo-Cardio-Facial syndrome). Here, we show in a family-based sample that functional polymorphisms in PRODH are associated with schizophrenia, with protective...

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Detalhes bibliográficos
Main Authors: Kempf, Lucas, Nicodemus, Kristin K., Kolachana, Bhaskar, Vakkalanka, Radhakrishna, Verchinski, Beth A., Egan, Michael F., Straub, Richard E., Mattay, Venkata A., Callicott, Joseph H., Weinberger, Daniel R., Meyer-Lindenberg, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573019/
https://ncbi.nlm.nih.gov/pubmed/18989458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000252
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