Induction of tumor necrosis factor (TNF) and interleukin-1 (IL-1) by Pseudomonas aeruginosa and exotoxin A-induced suppression of lymphoproliferation and TNF, lymphotoxin, gamma interferon, and IL-1 production in human leukocytes.

Pseudomonas aeruginosa is a dominant pathogen in infection in cystic fibrosis. This bacterium is thought to play a major role in the chronic bronchial infection-induced pathophysiology. Our data showed that whole formalin-fixed heat-killed P. aeruginosa was mitogenic for human lymphocytes and induce...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Staugas, R E, Harvey, D P, Ferrante, A, Nandoskar, M, Allison, A C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257297/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1639487/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.8.3162-3168.1992
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