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Construction of a multivalent meningococcal vaccine strain based on the class 1 outer membrane protein.

Outer membrane complexes (OMCs) are promising vaccine candidates for protection against meningococcal disease. However, a major obstacle to this approach is the fact that the protective antibodies induced are generally type specific. In an attempt to overcome this problem, we have investigated the p...

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Опубликовано в: :Infect Immun
Главные авторы: Van Der Ley, P, Poolman, J T
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1992
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257296/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1639486/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.8.3156-3161.1992
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