Microdialysis Elevation of Adenosine in the Basal Forebrain Produces Vigilance Impairments in the Rat Psychomotor Vigilance Task

STUDY OBJECTIVE: The inhibitory neuromodulator adenosine has been proposed as a homeostatic sleep factor that acts potently in the basal forebrain (BF) to increase sleepiness. Here 300 μM of adenosine was dialyzed in the BF of rats, and the effect on vigilance was determined in the rat Psychomotor V...

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Hlavní autoři: Christie, Michael A., Bolortuya, Yunren, Chen, Li Chao, McKenna, James T., McCarley, Robert W., Strecker, Robert E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Associated Professional Sleep Societies, LLC 2008
Témata:
Basal Forebrain Adenosine and PVT Performance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572744/
https://ncbi.nlm.nih.gov/pubmed/18853936
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