The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells

The protein product of the ocular albinism type 1 gene, named OA1, is a pigment cell-specific G protein-coupled receptor exclusively localized to intracellular organelles, namely lysosomes and melanosomes. Loss of OA1 function leads to the formation of macromelanosomes, suggesting that this receptor...

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Main Authors: Palmisano, Ilaria, Bagnato, Paola, Palmigiano, Angela, Innamorati, Giulio, Rotondo, Giuseppe, Altimare, Domenico, Venturi, Consuelo, Sviderskaya, Elena V., Piccirillo, Rosanna, Coppola, Massimiliano, Marigo, Valeria, Incerti, Barbara, Ballabio, Andrea, Surace, Enrico M., Tacchetti, Carlo, Bennett, Dorothy C., Schiaffino, Maria Vittoria
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572695/
https://ncbi.nlm.nih.gov/pubmed/18697795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn241
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