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Classification of drug molecules considering their IC(50 )values using mixed-integer linear programming based hyper-boxes method

BACKGROUND: A priori analysis of the activity of drugs on the target protein by computational approaches can be useful in narrowing down drug candidates for further experimental tests. Currently, there are a large number of computational methods that predict the activity of drugs on proteins. In thi...

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Detalhes bibliográficos
Main Authors: Armutlu, Pelin, Ozdemir, Muhittin E, Uney-Yuksektepe, Fadime, Kavakli, I Halil, Turkay, Metin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572625/
https://ncbi.nlm.nih.gov/pubmed/18834515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-411
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