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Propionate induces polymorphonuclear leukocyte activation and inhibits formylmethionyl-leucyl-phenylalanine-stimulated activation.

Short-chain carboxylic acids (SCCA) are metabolic by-products of bacterial pathogens which can alter cytoplasmic pH and inhibit a variety of polymorphonuclear leukocyte (PMN) motile functions. Since cytoskeletal F-actin alterations are central to PMN mobility, in this study we examined the effects o...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Brunkhorst, B A, Kraus, E, Coppi, M, Budnick, M, Niederman, R
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257260/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1319407/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.7.2957-2968.1992
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