Derepressed Hyphal Growth and Reduced Virulence in a VH1 Family-related Protein Phosphatase Mutant of the Human Pathogen Candida albicans

Mitogen-activated protein (MAP) kinases are pivotal components of eukaryotic signaling cascades. Phosphorylation of tyrosine and threonine residues activates MAP kinases, but either dual-specificity or monospecificity phosphatases can inactivate them. The Candida albicans CPP1 gene, a structural mem...

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Bibliographic Details
Main Authors: Csank, Csilla, Makris, Constantin, Meloche, Sylvain, Schröppel, Klaus, Röllinghoff, Martin, Dignard, Daniel, Thomas, David Y., Whiteway, Malcolm
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC25726/
https://ncbi.nlm.nih.gov/pubmed/9398674
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