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Increased Proteasome-Dependent Degradation of Estrogen Receptor-Alpha by TGF-β1 in Breast Cancer Cell Lines

Normal mammary epithelial cells are rapidly induced to G(1) arrest by the widely expressed cytokine, transforming growth factor beta (TGF-β1). Studies in established breast cancer cell lines that express the estrogen receptor alpha (ERα) have demonstrated loss of this responsiveness. This inverse co...

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Bibliografiske detaljer
Main Authors: Petrel, Trevor A., Brueggemeier, Robert W.
Format: Artigo
Sprog:Inglês
Udgivet: 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572568/
https://ncbi.nlm.nih.gov/pubmed/12461787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.10353
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