Construction of Cu-Zn superoxide dismutase deletion mutants of Brucella abortus: analysis of survival in vitro in epithelial and phagocytic cells and in vivo in mice.

Cu-Zn superoxide dismutase (SOD) deletion mutants of Brucella abortus S2308, a virulent strain, and S19, a vaccine strain, were generated by gene replacement. A deletion plasmid, pBA delta sodknr, was constructed by excising the Cu-Zn SOD gene (Cu-Zn sod) from a 2.3-kb B. abortus DNA fragment of pla...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Tatum, F M, Detilleux, P G, Sacks, J M, Halling, S M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257246/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1612752/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.7.2863-2869.1992
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