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Reactivation of model cholinesterases by oximes and intermediate phosphyloximes: A computational study
Phosphyloximes (POX) are generated upon the reactivation of organophosphorus (OP) inhibited cholinesterases (ChEs) by pyridinium oximes. These POXs are known to be potent inhibitors of the ChEs following reactivation. However, they can also decompose to give an OP derivative and a cyano derivative o...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2572230/ https://ncbi.nlm.nih.gov/pubmed/18582852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2008.05.006 |
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