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Characterization of a Lipid Hydroperoxide-Derived RNA-Adduct in Rat Intestinal Epithelial Cells

Five major products (adducts A(1a), A(1b), A(2), A(3,)and B) from the reaction of guanosine (Guo) with 4-oxo-2(E)-nonenal (ONE) were detected by liquid chromatography-mass spectrometry (LC-MS). Tandem MS (MS/MS) analysis of these compounds suggested that modifications to the nucleoside had been intr...

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Bibliografiske detaljer
Main Authors: Zhu, Peijuan, Lee, Seon Hwa, Wehrli, Suzanne, Blair, Ian A.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572167/
https://ncbi.nlm.nih.gov/pubmed/16780360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx0600189
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