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Comparable contributions of structural-functional constraints and expression level to the rate of protein sequence evolution

BACKGROUND: Proteins show a broad range of evolutionary rates. Understanding the factors that are responsible for the characteristic rate of evolution of a given protein arguably is one of the major goals of evolutionary biology. A long-standing general assumption used to be that the evolution rate...

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Main Authors: Wolf, Maxim Y, Wolf, Yuri I, Koonin, Eugene V
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572155/
https://ncbi.nlm.nih.gov/pubmed/18840284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-3-40
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