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OutFOXOing disease and disability: the therapeutic potential of targeting FoxO proteins
Forkhead transcription factors have a ‘winged helix’ domain and regulate processes that range from cell longevity to cell death. Of the mammalian forkhead family members in the O class, FoxO1, FoxO3a and FoxO4 can fill a crucial void for the treatment of disorders that include aging, cancer, diabete...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2572150/ https://ncbi.nlm.nih.gov/pubmed/18403263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2008.03.002 |
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