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The MLH1 -93 G>A Promoter Polymorphism and Genetic and Epigenetic Alterations in Colon Cancer

The MLH1 -93 G>A promoter polymorphism has been reported to be associated with an increased risk of microsatellite unstable colorectal cancer. Other than microsatellite instability, however, the genetic and most epigenetic changes of tumors associated with this polymorphism have not been studied....

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Detalhes bibliográficos
Main Authors: Samowitz, Wade S., Curtin, Karen, Wolff, Roger K., Albertsen, Hans, Sweeney, Carol, Caan, Bette J., Ulrich, Cornelia M., Potter, John D., Slattery., Martha L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572137/
https://ncbi.nlm.nih.gov/pubmed/18615680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20584
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